ea0063p222 | Diabetes, Obesity and Metabolism 1 | ECE2019
Valdes-Socin Hernan
, Vranken Laura
, Schoneveld Lauranne
, Delannoy Pauline
, Goff Caroline Le
, Beckers Albert
, Cavalier Etienne
Introduction: Increased B12 deficiency among T2DM patients using metformin has been reported. Holotranscobalamin (HoloTc), the bioactive form of B12, is proposed as a specific and sensitive marker of B12 deficiency. Methods to evaluate vitamin B12 deficiency in these patients remain controversial.Methods: First, we studied the prevalence of vitamin B12 deficiency in a group of 106 T2DM patients treated by Metformin, not supplemented by B12. Antacids were...